Sinister syndicate

A group of supervillains who band together to defeat Spider-Man.

Vulture/Adrian Toomes  - An elderly scientist who donned a vulture flight suite to take revenge against those whom he'd claimed to have spurned and rejected him.

Sandman/Flint Marko - A petty crook with the ability to turn himself into sand.

Electro/Max Dillon - Once, he was an electrician and a friend of the Parkers, until a freak accident caused his body to become living electricity.

Chameleon, master of disguise - He wears a shifting belt to capturing an image of any person, so that he can turn into that person.

Shocker/Herman Schultz - A mugger turned mercenary who fires electric bolts and compressed air from his gauntlets.

Doctor Octopus/Otto Octavius - A highly intelligent scientist who utilizes four powerful, mechanical appendages.

Mysterio/Quentin Beck - Master hypnotist and special effects, and illusion expert.  

Rhino/Alexander O'Hirn - A man with a Rhino suit that grants high-level resistance to temperature and damage.